Introduction:
SPNIB 50 TABLET contains Dasatinib which belongs to the group of medicines called Tyrosine Kinase Inhibitor. It is used to treat cancers of blood and bone marrow (such as chronic myeloid leukaemia (CML) or Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia) in adults, adolescents and in children (aged 1 year or above).
It is primarily used in patients when treatment with conventional therapies is not suitable or fails to provide adequate response.
Leukaemia is the cancer of blood cells. It is caused due to abnormal growth and multiplication of blood cells within the bone marrow. It is characterized by severe tiredness, breathlessness, increased bleeding tendency, tiredness, anemia, night sweats, fever, chills, frequent infections and weight loss.
Instructions:
Your doctor or nurse will give you this medicine. Kindly do not self administer.Side Effects:
COMMON
- Increased infections
- Nausea, vomiting
- Diarrhea, stomach pain, bloating, constipation, heartburn
- Lack of appetite, changes in taste
- Mouth ulcers, hair loss
- Weight loss or weight gain
- Headache, tiredness, weakness
- Dizziness
- Skin rash, itching, dry skin, acne
- Increased bleeding tendency
- Joint pain, muscle pain or spasms
- Increased sweating, flushing
- Blurred vision, dry eyes
- Depression, sleeplessness
- Oedema (swelling of body parts)
UNCOMMON
- Irregular heartbeat, chest pain, breathing difficulties
- Stomach ulcers, inflammation of the food pipe
- Swollen tummy, anal tears
- Anxiety, confusion, mood swings, memory loss
- Low sexual drive
- Loss of hearing, sensitivity to light
- Skin inflammation, nail disorder
- Problems in passing urine
- Breast enlargement in men, menstrual disorder
- High blood cholesterol levels
- Swollen lymph nodes
- Increased protein in the urine
RARE
Stop taking SPNIB 50 TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- Signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- Chest pain, cough, breathing difficulties and fainting (signs of fluid retention in lungs)
- Unusual bleeding or bruising with fever, tiredness and confusion (signs of blood vessel damage)
- Bloody stools/urine/vomit or black tarry stools
- Blistering or peeling of skin and mucous membranes with fever and sore throat, mouth ulcers
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