Introduction:
CYCLOXAN 1GM INJECTION contains Cyclophosphamide, which belongs to a group of medicines called Alkylating agents. It is used in the treatment of malignant diseases in adults and children such as malignant lymphomas (Stages III and IV), Hodgkin’s disease, Non-Hodgkin’s lymphoma, lymphocytic lymphoma (nodular or diffuse), mixed-cell type lymphoma, histiocytic lymphoma, Burkitt’s lymphoma, multiple myeloma, chronic lymphocytic leukemia, chronic granulocytic leukemia, acute myelogenous leukemia, monocytic leukemia and acute lymphoblastic leukemia, mycosis fungoides, neuroblastoma, adenocarcinoma of the ovary, retinoblastoma, Ewing’s sarcoma, breast cancer.
CYCLOXAN 1GM INJECTION is also indicated for the treatment of nephrotic syndrome in children who fail to adequately respond to or are unable to tolerate adrenocorticosteroid therapy.
CYCLOXAN 1GM INJECTION is not recommended for use in patients with acute infections, bone-marrow aplasia and urinary tract infections like cystitis, acute urothelial toxicity from cytotoxic chemotherapy or radiation therapy or urinary outflow obstruction.
Instructions:
Your doctor or nurse will give you this medicine. Kindly do not self administer.Side Effects:
- Nausea, vomiting, weight loss
- Alopecia (loss of hair)
- Hematuria
- Leukopenia
- Diarrhea
- Darkening of skin/fingernails
- Stomatitis, anorexia
- Headache
- Diaphoresis
- SIADH, gonadal suppression
- Hyperuricemia
- Impaired wound healing
- Amenorrhea, premature menopause, sterility
- Allergic reactions such as anaphylaxis, swelling of the face, lips, ankles/legs causing shortness of breath
- Palpitations
- Weight gain, dizziness or loss of consciousness
- Signs of infection include fever, sore throat, cold and cough
- Signs of bleeding from gums, bruising and petechiae due to a decrease in platelet count
- Haematuria (blood in urine)
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