TEMCAD 100MG CAP (5'S STRIP)

Introduction:

TEMCAD 100MG CAPSULE contains Temozolomide which belongs to the group of medicines called Antineoplastic agents.

TEMCAD 100MG CAPSULE is used to treat specific forms of brain tumors in adults with newly diagnosed glioblastoma multiforme which is used first together with radiotherapy as a concomitant phase of therapy and then used alone as a monotherapy.

It is also used in children (above 3 years) and adults to treat malignant gliomas, such as glioblastoma multiforme or anaplastic astrocytoma if they return or get worse after standard treatment.

Glioblastoma multiforme is an aggressive type of cancer that affects the brain or spinal cord and is generally characterized by symptoms such as headache, nausea, drowsiness, blurred vision, personality changes, and seizures.

Along with this treatment, your doctor might advise you to take liver function tests to assess the hepatotoxicity (injury to the liver due to exposure to drugs) and function of your liver.

Before taking TEMCAD 100MG CAPSULE, inform your doctor if you have or ever had a hepatitis B infection (serious liver infection).

TEMCAD 100MG CAPSULE is not recommended for use if you have certain kinds of blood cells which are severely reduced such as white blood cell and platelet count.

TEMCAD 100MG CAPSULE should be used with caution during pregnancy only if it is clearly necessary and not recommended for use in breastfeeding women.

It is not recommended for use in children below 3 years of age and should be used with caution in children and adolescents (from 3 to 18 years of age). Consult your doctor before taking TEMCAD 100MG CAPSULE. The most common side effects of taking TEMCAD 100MG CAPSULE are loss of appetite, difficulty while speaking, headache, vomiting, nausea, diarrhea, and constipation. Consult and inform your doctor if any of these symptoms get worse.

Instructions:

Take TEMCAD 100MG CAPSULE as advised by your physician. Swallow TEMCAD 100MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects:

COMMON

• Loss of Appetite
• Difficulty while speaking
• Headache
• Vomiting, Nausea
• Diarrhea
• Constipation
• Rash
• Hair loss
• Tiredness
• Infections, oral infections
• Feeling sick, extremely tiredness, loss of appetite (signs of neutropenia)
• Fever, cough, runny nose (signs of lymphopenia)
• Prolonged cuts, bleeding from gums, blood in the urine (signs of thrombocytopenia)
• Allergic reactions
• Memory impairment
• Depression, anxiety, confusion, sleeplessness
• Difficulty concentrating
• Dizziness
• Visual disturbances
• Deafness, ringing in the ears, earache
• Blood clot in lung or legs
• High blood pressure
• Shortness of breath
• Bronchitis
• Cough and cold
• Inflammation of your sinuses
• Stomach or abdominal pain
• Dry skin, itching
• Muscle damage, muscle aches, and pain, muscle weakness
• Joint and back pain
• Frequent urination
• Fever
• Flu-like symptoms such as chills, cough, fever, muscle aches
• Pain
• Fluid retention
• Weight gain or loss
• Radiation injuries such as weakness, hair loss, and bloody vomit

UNCOMMON

• New or reactivated cytomegalovirus infections such as chickenpox, herpes simplex
• Signs of reactivated hepatitis b virus infections such as abdominal pain, dark urine, fever, and joint pain
• Secondary cancers including leukemia (blood cancer)
• Reduced blood cell counts such as pancytopenia
• Red spots under the skin
• Signs of diabetes insipidus
• Piles
• Dry mouth
• Blisters on the body or in the mouth
• Skin peeling, skin eruption, painful reddening of the skin, a severe rash with skin swelling
• Increased sensitivity to sunlight
• Urticaria (red, itchy skin)
• Increased sweating
• Change in skin color
• Vaginal bleeding or irritation
• Absent or heavy menstrual periods
• Breast pain
• Sexual impotence
• Shivering

RARE
Stop taking TEMCAD 100MG CAPSULE and contact your doctor if you experience any of the following side effects:

• Signs of a severe allergic (hypersensitive) reaction such as itchy red skin, wheezing or another breathing difficulty
• Uncontrolled bleeding
• Seizures (fits)
• Fever and symptoms of infections such as cough, chills, sweat
• Chills
• Severe headache