AZASHINE 100MG VIAL

Introduction:

Azashine Injection is an anticancer medication used to treat Myelodysplastic Syndrome (MDS), a group of disorders where the bone marrow produces abnormal blood cells, which can lead to low levels of healthy blood cells. This Azashine belongs to a class of medications called demethylation agents, which work by inhibiting DNA methylation, a process that can lead to abnormal gene expression and cellular dysfunction. By inhibiting DNA methylation, Azashine can help to restore normal gene expression and promote the growth of healthy blood cells while killing abnormal cells in the bone marrow. Azashine 100 mg Injection is typically given as an injection under the skin or into a vein over a period of several days. The safety and effectiveness of Azashine Injection in children and adolescents have not been established.

If you experience injection site reactions such as pain, swelling, or redness, as well as Vomiting, Weakness, or Nausea, when taking this Azashine, please inform your doctor as these are the most frequently reported side effects. Your doctor may be able to provide suggestions for reducing or preventing these side effects. Additionally, if you are receiving treatment with this Azashine, you must inform your doctor before receiving any vaccinations. Regular blood tests will be necessary to monitor your blood cells, as well as the health of your heart, liver, and kidneys.

Patients who have a known Allergy to Azashine and its components should avoid using Azashine Injection. Additionally, it is not recommended for patients with advanced malignant hepatic tumours as it may worsen the disease.

Before taking Azashine Injection, you should inform your doctor of any pre-existing medical conditions, such as heart disease, liver or kidney problems, or if you are currently taking any other medications, including prescription drugs, over-the-counter medications, vitamins, and herbal remedies. This is because Azashine may interact with other medications and result in adverse effects. Your doctor may need to adjust your dosage or closely monitor you for any side effects. The use of Azashine Injection is not recommended for pregnant or breastfeeding women, as it may cause harm to the developing fetus or newborn. Women of childbearing age should utilize effective contraception during treatment to prevent pregnancy.

Azashine Injection should be given either intravenously or intramuscularly. Your doctor will determine the appropriate dosage and frequency of administration based on the severity of your condition, which may be subject to change. It is important to follow your doctor's instructions for taking Azashine, as improper or excessive intake may lead to severe adverse effects. Although it may take several weeks or months to observe the benefits of the medication, it is essential not to discontinue treatment unless your doctor tells you to.

Instructions:

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Myelodysplastic Syndromes (MDS): Azashine 100 mg Injection indicated for the treatment of myelodysplastic syndromes (MDS), which is a group of disorders that affect the bone marrow and blood cells. Myelodysplastic Syndrome is characterized by the production of abnormal, immature blood cells called blasts instead of mature cells. These blasts do not function correctly, leading to symptoms such as anemia, easy bruising or bleeding, and an increased risk of infections.

Azashine Injection should be given either intravenously or intramuscularly. Your doctor will determine the appropriate dosage and frequency of administration based on the severity of your condition, which may be subject to change. It is important to follow your doctor's instructions for taking Azashine, as improper or excessive intake may lead to severe adverse effects. Although it may take several weeks or months to observe the benefits of the medication, it is essential not to discontinue treatment unless instructed to do so by your doctor.

Safety Advices 
Pregnancy

• UNSAFE Use of Azashine Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Azashine during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health. 

Alcohol

• UNSAFE It is generally not recommended to drink alcohol while taking Azashine. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication. 

Breastfeeding

• UNSAFE It is not recommended to breastfeed while taking Azashine. Azashine Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Azashine 100 mg Injection, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Liver

• USE WITH CAUTION Azashine Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Azashine 100 mg Injection and report any unusual symptoms or changes in liver function to their doctor. The dose of Azashine may need to be adjusted in patients with liver disease. 

Kidney

• USE WITH CAUTION Azashine 100 mg Injection should be used with caution in patients with Kidney disease. It is important that patients with kidney disease closely monitor kidney function while taking Azashine Injection and report any unusual symptoms or changes in kidney function to their doctor. The dose of Azashine may need to be adjusted in patients with kidney disease. 

Driving

• UNSAFE Azashine Injection may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Azashine 100 mg Injection.

Side Effects:

Most Common Side Effects of Azashine Injection

• Constipation
• Joint Pain
• Rashes
• Tiredness
• Stomach Pain
• Nausea
• Skin irritation and redness at the injection site

Common Side Effects of Azashine Injection

• Pneumonia
• Burning sensation during urination
• High fever
• Blood in urine and stool
• Seizures
• Lips swelling and Rashes